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Proteintech
PDE10A Polyclonal Antibody
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产品信息
18078-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse
已发表种属
Bovine,
Cat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PDE10A Fusion Protein Ag12771 (434-779 aa encoded by BC104860)
偶联物
形式
Liquid
浓度
0.19 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: KLSYHSICT SEEWQGLMQF TLPVRLCKEI ELFHFDIGPF ENMWPGIFVY MVHRSCGTSC FELEKLCRFI MSVKKNYRRV PYHNWKHAVT VAHCMYAILQ NNHTLFTDLE RKGLLIACLC HDLDHRGFSN SYLQKFDHPL AALYSTSTME QHHFSQTVSI LQLEGHNIFS TLSSSEYEQV LEIIRKAIIA TDLALYFGNR KQLEEMYQTG SLNLNNQSHR DRVIGLMMTA CDLCSVTKLW PVTKLTANDI YAEFWAEGDE MKKLGIQPIP MMDRDKKDEV PQGQLGFYNA VAIPCYTTLT QILPPTEPLL KACRDNLSQW EKVIRGEETA TWISSPSVAQ KAAASED (434-779 aa encoded by BC104860 )
靶标信息
Various cellular responses are regulated by the second messengers cAMP and cGMP. Phosphodiesterases, such as PDE10A, eliminate cAMP- and cGMP-mediated intracellular signaling by hydrolyzing the cyclic nucleotide to the corresponding nucleoside 5-prime monophosphate.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A; dual-substrate cAMP and cGMP, cyclic nucleotide phosphodiesterase; FLJ11894; FLJ25677; PDE10A2 brain-specific isoform
基因别名: Pde10a
UniProt ID: (Mouse) Q8CA95
Entrez Gene ID: (Mouse) 23984
nucleotide binding
catalytic activity
cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-nucleotide phosphodiesterase activity
cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
phosphoric diester hydrolase activity
drug binding
hydrolase activity
cAMP binding
cGMP binding
metal ion binding
3',5'-cyclic-GMP phosphodiesterase activity
phosphodiesterase
