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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫组化 (IHC) |
1:50-1:200 | - |
免疫细胞化学 (ICC/IF) |
0.25-2 µg/mL | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant protein corresponding to Human PDE1C |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.1 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.2, with 40% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2645326 |
Immunogen sequence: EEQQKEMEAK SQAEEGASGK AEKKTSGETK NQVNGTRANK SDNPRGKNSK AEKSSGEQQQ NGDFKDGK
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 78%.
Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin -dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 ).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 3',5'-cyclic-AMP phosphodiesterase; 3',5'-cyclic-GMP phosphodiesterase; Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C; Cam-PDE 1C; Hcam3; Human 3',5' cyclic nucleotide phosphodiesterase (HSPDE1C1A); phosphodiesterase 1C, calmodulin-dependent 70kDa
基因别名: cam-PDE 1C; hCam-3; Hcam3; PDE1C
UniProt ID: (Human) Q14123
Entrez Gene ID: (Human) 5137
分子生物学功能:
phosphodiesterase
