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Fabgennix
PDE4B4 Polyclonal Antibody
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图: 1 / 1
PDE4B4 Antibody (PD4B4-231AP) in WB
WB of PD4B4-231AP showing changes in PDE4B4 variant. Lanes 1 and 2 are left and right testis from control rat. Lanes 3, 5, and 7 are the left contralateral control scrotal testis; lanes 4, 6, and 8 are the right abdominal testis from 10-, 20-, and 30-day cryptorchid rats, respectively.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PD4B4-231AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide selective only for PDE4B4 protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3',5'-cyclic AMP phosphodiesterase; cAMP phosphodiesterase; cAMP specific; cAMP-specific 3',5'-cyclic phosphodiesterase 4B; cAMP-specific phosphodiesterase 4B; DPDE4; dunce-like phosphodiesterase E4; Pde4b; PDE4B5; phosphodiesterase 4B, cAMP specific; Phosphodiesterase 4B, cAMP-specific (dunce; phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila); phosphodiesterase type 4B5; similar to Pde4b3; unnamed protein product
基因别名: DPDE4; dunce; PDE4/IVb; Pde4B1; Pde4B2; Pde4B3; Pde4B4; Pde4b5; Pde4b_v1; Pde4b_v2; Pde4b_v3; Pde4b_v4; PDEIVB
UniProt ID: (Human) Q07343, (Rat) P14646
Entrez Gene ID: (Human) 5142, (Mouse) 18578, (Rat) 24626
neutrophil homeostasis
cAMP catabolic process
signal transduction
neutrophil chemotaxis
positive regulation of interferon-gamma production
positive regulation of interleukin-2 production
T cell receptor signaling pathway
leukocyte migration
cellular response to lipopolysaccharide
cellular response to xenobiotic stimulus
cellular response to epinephrine stimulus
negative regulation of adrenergic receptor signaling pathway
regulation of cardiac muscle cell contraction
negative regulation of cAMP/PKA signal transduction
negative regulation of relaxation of cardiac muscle
regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
