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Invitrogen
PDGFRA Polyclonal Antibody
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产品信息
PA1-24835
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant, full length human protein.
偶联物
形式
Liquid
浓度
0.1 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
PA1-24835 detects PDGF Receptor alpha from human samples.
PA1-24835 has been successfully used in neutralization, inhibition assays, and Western blot procedures. Neutralization: The ND50 is 5-15 µg/mL.
The PA1-24835 immunogen is recombinant, full length human protein.
靶标信息
PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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