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Proteintech
PDGFRL Polyclonal Antibody
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产品信息
16217-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PDGFRL Fusion Protein Ag9218 (1-375 aa encoded by BC010927)
偶联物
形式
Liquid
浓度
0.45 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MKVWLLLGL LLVHEALEDV TGQHLPKNKR PKEPGENRIK PTNKKVKPKI PKMKDRDSAN SAPKTQSIMM QVLDKGRFQK PAATLSLLAG QTVELRCKGS RIGWSYPAYL DTFKDSRLSV KQNERYGQLT LVNSTSADTG EFSCWVQLCS GYICRKDEAK TGSTYIFFTE KGELFVPSPS YFDVVYLNPD RQAVVPCRVT VLSAKVTLHR EFPAKEIPAN GTDIVYDMKR GFVYLQPHSE HQGVVYCRAE AGGRSQISVK YQLLYVAVPS GPPSTTILAS SNKVKSGDDI SVLCTVLGEP DVEVEFTWIF PGQKDERPVT IQDTWRLIHR GLGHTTRISQ SVITVEDFET IDAGYYICTA QNLQGQTTVA TTVEFS (1-375 aa encoded by B C010927)
靶标信息
PDGFRL bears significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in the PDGFRL gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests PDGFRL may function as a tumor suppressor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: PDGF receptor beta-like tumor suppressor; PDGFR-like protein; Platelet-derived growth factor receptor-like protein; platelet-derived growth factor-beta-like tumor suppressor
基因别名: 1110039P19Rik; AV013190; PDGFRL; PDGRL; PRLTS
UniProt ID: (Human) Q15198, (Mouse) Q6PE55, (Rat) Q5RJP7
Entrez Gene ID: (Human) 5157, (Mouse) 68797, (Rat) 290771
