Search Thermo Fisher Scientific
Immunogen sequence: ESPESSAIES TQSTPQKGRG RPSKTPSPSQ PKKNVRVGRS KQAATKENDS SEEVDVFQGS SPVDDIPQEE TEEEEVSTVN VRRRSAKRER
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 81%.
This gene encodes a protein that interacts with the conserved protein complex termed cohesin. The cohesin complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor-suppressor gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: androgen induced inhibitor of proliferation; Androgen-induced proliferation inhibitor; Androgen-induced prostate proliferative shutoff-associated protein AS3; androgen-induced shutoff 3; Sister chromatid cohesion protein PDS5 homolog B
基因别名: APRIN; AS3; CG008; KIAA0979; PDS5B
UniProt ID: (Human) Q9NTI5
Entrez Gene ID: (Human) 23047
分子生物学功能: chromatin/chromatin-binding, or -regulatory protein