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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
PDSS1 is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. PDSS1 catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in PDSS1 gene are a cause of coenzyme Q10 deficiency.The protein encoded by this gene is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in this gene are a cause of coenzyme Q10 deficiency.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: all-trans-decaprenyl-diphosphate synthase subunit 1; coenzyme Q1 homolog; decaprenyl pyrophosphate synthase subunit 1; MGC70953; polyprenyl pyrophosphate synthetase; prenyl (decaprenyl) diphosphate synthase, subunit 1; RP13-16H11.3; solanesyl-diphosphate synthase subunit 1; subunit 1 of decaprenyl diphosphate synthase; TPT; polyprenyl pyrophosphate synthetase; trans-prenyltransferase (TPT); trans-prenyltransferase 1; unnamed protein product
基因别名: COQ1; COQ10D2; COQ1A; DPS; hDPS1; SPS; TPRT; TPT; TPT 1
UniProt ID: (Human) Q5T2R2
Entrez Gene ID: (Human) 23590