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Invitrogen
PDZRN3 Polyclonal Antibody
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产品信息
PA5-117726
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
C. elegans
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human E3 ubiquitin-protein ligase PDZRN3 protein (133-404aa)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody has been tested in direct-ELISA
靶标信息
E3 ubiquitin-protein ligase. Plays an important role in regulating the surface level of MUSK on myotubes. Mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. Might contribute to terminal myogenic differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: E3 ubiquitin-protein ligase PDZRN3; Ligand of Numb protein X 3; likely ortholog of mouse semaF cytoplasmic domain associated protein 3; PDZ domain containing RING finger 3A; PDZ domain-containing RING finger protein 3; Protein SEMACAP3; RING-type E3 ubiquitin transferase PDZRN3; Semaphorin cytoplasmic domain-associated protein 3; semaphorin cytoplasmic domain-associated protein 3A
基因别名: 1110020C07Rik; AI429718; AL023082; KIAA1095; LNX3; PDZRN3; SEMACAP3; SEMCAP3
UniProt ID: (Human) Q9UPQ7, (Mouse) Q69ZS0
Entrez Gene ID: (Human) 23024, (Mouse) 55983
ubiquitin-protein transferase activity
zinc ion binding
ligase activity
ubiquitin protein ligase activity
protein binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
scaffold/adaptor protein
