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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
3-7 µg/mL | - |
| 产品规格 | |
|---|---|
种属反应 |
Bovine, Dog, Horse, Human, Marsupial, Mouse, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthetic peptide (2 NLERVSNEEKLNLCRKYY 19) of Presenilin enhancer protein 2 protein. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.5 mg/mL |
纯化类型 |
Protein A |
保存液 |
PBS with 0.05% BSA |
内含物 |
0.05% sodium azide |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2540947 |
Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Gamma-secretase subunit PEN-2; hematopoietic stem/progenitor cells protein MDS033; Liver regeneration-related protein LRRGT00140; LRRGT00140 mRNA; presenilin enhancer 2 homolog; presenilin enhancer gamma secretase subunit; Presenilin enhancer protein 2
基因别名: 1700023M09Rik; MDS033; MSTP064; PEN-2; PEN2; PSENEN; RGD1312037
UniProt ID: (Human) Q9NZ42, (Bovine) Q5G235, (Mouse) Q9CQR7, (Rat) Q6QI68
Entrez Gene ID: (Human) 55851, (Dog) 476479, (Bovine) 493993, (Horse) 100051536, (Mouse) 66340, (Rat) 292788
