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Proteintech
PEX14 Polyclonal Antibody
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产品信息
10594-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
已发表种属
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PEX14 Fusion Protein Ag0932 (77-377 aa encoded by BC006327)
偶联物
形式
Liquid
浓度
0.33 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody can be used to detect endogenous PEX14 with an apparent molecular weight of 57 kDa and recognize peroxisomal structures in human, monkey and mouse cells.
Immunogen sequence: PSSLGPATQ VVPVQPPHLI SQPYSPAGSR WRDYGALAII MAGIAFGFHQ LYKKYLLPLI LGGREDRKQL ERMEAGLSEL SGSVAQTVTQ LQTTLASVQE LLIQQQQKIQ ELAHELAAAK ATTSTNWILE SQNINELKSE INSLKGLLLN RRQFPPSPSA PKIPSWQIPV KSPSPSSPAA VNHHSSSDIS PVSNESTSSS PGKEGHSPEG STVTYHLLGP QEEGEGVVDV KGQVRMEVQG EEEKREDKED EEDEEDDDVS HVDEEDCLGV QREDRRGGDG QINEQVEKLR RPEGASNESE RD (77-377 aa encoded by BC006327)
靶标信息
PEX14 belongs to the peroxin 14 family. It is a component of the peroxisomal translocation machinery with PEX13 and PEX17 and interacts with both the PTS1 and PTS2 receptors. PEX14 binds directly to PEX17. Defects in PEX14 are the cause of peroxisome biogenesis disorder complementation group K (PBD-CGK) and Zellweger syndrome (ZWS).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: NF-E2 associated polypeptide 2; Peroxin 14; Peroxin-14; Peroxisomal membrane anchor protein PEX14; peroxisomal membrane anchor protein Pex14p; Peroxisomal membrane protein PEX14; peroxisomal protein Pex14; PEXE; PTS1 receptor docking protein; PTS1 receptor-docking protein
基因别名: dJ734G22.2; NAPP2; PBD13A; PEX14; Pex14p; R75137
UniProt ID: (Human) O75381, (Mouse) Q9R0A0, (Rat) Q642G4
Entrez Gene ID: (Human) 5195, (Mouse) 56273, (Rat) 64460
protein complex assembly
peroxisome organization
protein import into peroxisome matrix
protein import into peroxisome matrix, translocation
negative regulation of protein binding
microtubule anchoring
peroxisome transport along microtubule
negative regulation of sequence-specific DNA binding transcription factor activity
protein import into peroxisome matrix, substrate release
negative regulation of transcription, DNA-templated
protein homooligomerization
negative regulation of protein homotetramerization
transport
protein transport
protein import into peroxisome matrix, docking
