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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
The PF4V1 (Platelet Factor 4 Variant 1) gene, located on chromosome 4q12, encodes a protein that is a member of the CXC chemokine family, sharing significant homology with platelet factor 4 (PF4/CXCL4). PF4V1 is primarily expressed in megakaryocytes and platelets, playing a role in modulating coagulation and inflammatory responses. The protein has chemotactic activity, attracting immune cells to sites of injury or inflammation. Furthermore, PF4V1 can bind to heparin, influencing the anticoagulant activity of heparin and potentially impacting hemostasis and thrombosis. Research suggests that variations in the expression or function of PF4V1 might contribute to different pathological conditions, including cardiovascular disease and inflammatory disorders.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C-X-C motif chemokine 4 variant; CXCL4L1; PF4alt; PF4var1; Platelet factor 4 variant
基因别名: CXCL4V1; PF4V1; SCYB4V1
Entrez Gene ID: (Human) 5197