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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: early development regulator 3; Early development regulatory protein 3; Homolog of polyhomeotic 3; hPH3; polyhomeotic 3; polyhomeotic like 3; Polyhomeotic-like protein 3
基因别名: E030046K01Rik; EDR3; HPH3; PH3; PHC3
UniProt ID: (Human) Q8NDX5, (Mouse) Q8CHP6
Entrez Gene ID: (Human) 80012, (Mouse) 241915
分子生物学功能: chromatin/chromatin-binding, or -regulatory protein