Search Thermo Fisher Scientific
Peptide Sequence: GRDSFEDEGR WCLILCATCG SHGTHRDCSS LRSNSKKWEC EECSPAAATD YIPENSGDIP CCSSTFHPEE HFCRDNTLEE NPGLSWTDWP EPSLLEKPES
Spermatogenesis is a complex process regulated by extracellular and intracellular factors as well as cellular interactions among interstitial cells of the testis, Sertoli cells, and germ cells. In the testis, this gene is expressed in Sertoli cells but not germ cells. However, this gene is not expressed in a patient who exhibited spermatogenic arrest at the spermatocyte stage. Spermatogenic arrest is an interruption of germ cell differentiation that may result in oligospermia or azoospermia. The proteins encoded by this gene contain plant homeodomain (PHD) finger domains, also known as leukemia associated protein (LAP) domains, believed to be involved in transcriptional regulation. Thus this protein, which localizes to the nucleus of transfected cells, has been implicated in the transcriptional regulation of spermatogenesis. Two protein isoforms are encoded by transcript variants of this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
Protein Aliases: PHD finger protein 7; testicular secretory protein Li 34; Testis development protein NYD-SP6
Gene Aliases: HSPC045; HSPC226; NYD-SP6; PHF7
UniProt ID: (Human) Q9BWX1
Entrez Gene ID: (Human) 51533
Molecular Function:
DNA metabolism protein
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support