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Product Details
MA5-21951
产品规格
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
1E9
Immunogen
PHF7 (NP_057567.3, 258 a.a. ~ 357 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated
形式
Liquid
浓度
0.2-1.0 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2605676
Product Specific Information
Peptide Sequence: GRDSFEDEGR WCLILCATCG SHGTHRDCSS LRSNSKKWEC EECSPAAATD YIPENSGDIP CCSSTFHPEE HFCRDNTLEE NPGLSWTDWP EPSLLEKPES
Target Information
Spermatogenesis is a complex process regulated by extracellular and intracellular factors as well as cellular interactions among interstitial cells of the testis, Sertoli cells, and germ cells. In the testis, this gene is expressed in Sertoli cells but not germ cells. However, this gene is not expressed in a patient who exhibited spermatogenic arrest at the spermatocyte stage. Spermatogenic arrest is an interruption of germ cell differentiation that may result in oligospermia or azoospermia. The proteins encoded by this gene contain plant homeodomain (PHD) finger domains, also known as leukemia associated protein (LAP) domains, believed to be involved in transcriptional regulation. Thus this protein, which localizes to the nucleus of transfected cells, has been implicated in the transcriptional regulation of spermatogenesis. Two protein isoforms are encoded by transcript variants of this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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Bioinformatics
Protein Aliases: PHD finger protein 7; testicular secretory protein Li 34; Testis development protein NYD-SP6
Gene Aliases: HSPC045; HSPC226; NYD-SP6; PHF7
UniProt ID: (Human) Q9BWX1
Entrez Gene ID: (Human) 51533
Molecular Function:
DNA metabolism protein
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