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Proteintech
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Immunogen sequence: MACLSPSQL QKFQQDGFLV LEGFLSAEEC VAMQQRIGEI VAEMDVPLHC RTEFSTQEEE QLRAQGSTDY FLSSGDKIRF FFEKGVFDEK GNFLVPPEKS INKIGHALHA HDPVFKSITH SFKVQTLARS LGLQMPVVVQ SMYIFKSPLI RTPPSCTRSP WAGCWACGSQ WRMPRWRTAV SGSSLAPTPV VCQGGWSGPL LAQRLVPASL GQSQPGITAS LCPPQCREGP WSSSMEKWYT RASRTSLTAR ARPTLSTSWR PLAPPGARRT GSSQQLNCPF PNCTPKGSRR AGALAPPG (1-297 aa encoded by BC009373)
PHYHD1 (phytanoyl-CoA dioxygenase domain containing 1) is a 291 amino acid protein belonging to the PHYH family and the PHYHD1 subfamily. Encoded by a gene that maps to human chromosome 9q34.11, PHYHD1 exists as three alternatively spliced isoforms and likely functions as an alpha-ketoglutatare-dependent dioxygenase. PHYHD1 participates in metal ion binding and oxidoreductase activity, thereby acting on single donors with incorporation of two atoms of oxygen. Related to PHYH (phytanoyl-CoA 2-hydroxylase), an Fe(II) and 2-oxoglutarate (2OG)-dependent oxygenase that catalyzes the initial alpha-oxidation step in the degradation of phytenic acid in peroxisomes, PHYHD1 similarly exhibits additional homologues in a wide range of metazoans and bacteria. PHYHD1 also may play a role in DNA methylation in early postnatal liver development and mammalian differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Phytanoyl-CoA dioxygenase domain-containing protein 1; Protein PHYHD1
基因别名: PHYHD1
UniProt ID: (Human) Q5SRE7, (Mouse) Q9DB26, (Rat) Q5BJP9
Entrez Gene ID: (Human) 254295, (Mouse) 227696, (Rat) 296621