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Proteintech
PI3 Kinase p85 Beta Polyclonal Antibody
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产品信息
25868-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PI3 Kinase p85 Beta fusion protein Ag14369
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: YRHESLAQYN AKLDTRLLYP VSKYQQDQIV KEDSVEAVGA QLKVYHQQYQ DKSREYDQLY EEYTRTSQEL QMKRTAIEAF NETIKIFEEQ GQTQEKCSKE YLERFRREGN EKEMQRILLN SERLKSRIAE IHESRTKLEQ QLRAQASDNR EIDKRMNSLK PDLMQLRKIR DQYLVWLTQK GARQKKINEW LGIKNETEDQ YALMEDEDDL PHHEERTWYV GKINRTQAEE MLSGKRDGTF LIRESSQRGC YACSVVVDGD TKHCVIYRTA TGFGFAEPYN LYGSLKELVL HYQHASLVQH NDALTVTLAH PVRAPGPGPP PAAR
靶标信息
Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta; phosphatidylinositol 3-kinase regulartory subunit polypeptide 2; Phosphatidylinositol 3-kinase regulatory subunit beta; phosphatidylinositol 3-kinase, regulartory subunit, polypeptide 2; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta); phosphoinositide-3-kinase regulatory subunit beta; phosphoinositide-3-kinase, regulatory subunit 2 (beta); PI3-kinase p85 subunit beta; PI3-kinase regulatory subunit beta; PI3-kinase subunit p85-beta; PI3K; PI3K regulatory subunit beta; ptdIns-3-kinase p85-beta; ptdIns-3-kinase regulatory subunit beta; ptdIns-3-kinase regulatory subunit p85-beta
基因别名: MPPH; MPPH1; p85; p85-BETA; P85B; p85beta; PIK3R2
UniProt ID: (Human) O00459, (Mouse) O08908
Entrez Gene ID: (Human) 5296, (Mouse) 18709, (Rat) 29741
GTPase activator activity
protein binding
1-phosphatidylinositol-3-kinase activity
protein phosphatase binding
receptor tyrosine kinase binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
1-phosphatidylinositol-3-kinase regulator activity
protein heterodimerization activity
transcription factor binding
phosphatidylinositol 3-kinase regulator activity
phosphatidylinositol 3-kinase regulatory subunit binding
kinase modulator
cellular glucose homeostasis
phosphatidylinositol biosynthetic process
insulin receptor signaling pathway
regulation of autophagy
phosphatidylinositol 3-kinase signaling
regulation of phosphatidylinositol 3-kinase signaling
protein transport
cellular response to insulin stimulus
response to endoplasmic reticulum stress
phosphatidylinositol-3-phosphate biosynthetic process
Fc-epsilon receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of transcription factor import into nucleus
positive regulation of GTPase activity
regulation of phosphatidylinositol 3-kinase activity
positive regulation of transcription from RNA polymerase II promoter
phosphatidylinositol phosphorylation
vascular endothelial growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling
T cell receptor signaling pathway
leukocyte migration
regulation of small GTPase mediated signal transduction
positive regulation of glucose import in response to insulin stimulus
transport
signal transduction
regulation of actin filament polymerization
regulation of phosphorylation
positive regulation of cell adhesion
regulation of stress fiber assembly
regulation of establishment of protein localization to plasma membrane
phosphorylation
