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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: AYSWQTDPNP NESHEKQYEH QEFLFVNQPH SSSQVSLGFD QIVDEISGKI PHYESEIDEN TFFVPTAPKW DSTGHSLNEA HQISLNEFTS KSRELSWHQ
PIK3C2G lipid kinase belongs to the phosphoinositide 3-kinase (PI3K) family which play major roles in signaling pathways and are involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. PIK3C2G contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases that act as calcium-dependent phospholipid binding motifs which mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The N-terminal region of PIK3C2G and the C-terminal C2 domain are required for enzymatic activity. The PI 3-kinase C2gamma gene encodes a 1,050 amino acid polypeptide with 36% identity to human PI 3-kinase C2alpha. Research indicates that PI 3-kinase C2gamma can block the growth of human colon cancer cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma; Phosphoinositide 3-kinase-C2-gamma; PI 3-kinase C2gamma; PI3K-C2-gamma; PI3KC2gamma
基因别名: PIK3C2G
Entrez Gene ID: (Human) 5288