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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
PIKFYVE belongs to a large family of lipid kinases that alter the phosphorylation status of intracellular phosphatidylinositol. The content of phosphatidylinositol 3,5-bisphosphateP2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. PIKFYVE is the PtdIns(3,5)P2-producing component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PIKFYVE activator VAC14 and the PtdIns(3,5)P2 phosphatase FIG4. In addition to its phosphoinositide 5-kinase activity, PIKFYVE also has protein kinase activity. For a review, see Shisheva.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 1-phosphatidylinositol 3-phosphate 5-kinase; FYVE finger-containing phosphoinositide kinase; Phosphatidylinositol 3-phosphate 5-kinase; Phosphatidylinositol 3-phosphate 5-kinase type III; PIKfyve; PIPkin-III; Serine-protein kinase PIKFYVE
基因别名: KIAA0981; PIKFYVE; PIP5K3
Entrez Gene ID: (Human) 200576