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Invitrogen
PIKFYVE Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-67981
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Zebrafish
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthesized peptide derived from human PIKFYVE.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol, 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Predicted to react with Mouse samples.
靶标信息
PIKFYVE belongs to a large family of lipid kinases that alter the phosphorylation status of intracellular phosphatidylinositol. The content of phosphatidylinositol 3,5-bisphosphateP2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. PIKFYVE is the PtdIns(3,5)P2-producing component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PIKFYVE activator VAC14 and the PtdIns(3,5)P2 phosphatase FIG4. In addition to its phosphoinositide 5-kinase activity, PIKFYVE also has protein kinase activity. For a review, see Shisheva.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 1-phosphatidylinositol 3-phosphate 5-kinase; 1-phosphatidylinositol-3-phosphate 5-kinase; FYVE finger-containing phosphoinositide kinase; p235; Phosphatidylinositol 3-phosphate 5-kinase; Phosphatidylinositol 3-phosphate 5-kinase type III; phosphatidylinositol-3-phosphate 5-kinase type III; phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III; phosphatidylinositol-4-phosphate 5-kinase, type III; PIKfyve; PIPkin-III; PtdIns(4)P-5-kinase; Serine-protein kinase PIKFYVE; type III PIP kinase
基因别名: 5230400C17Rik; Fab1; KIAA0981; p235; PIKFYVE; Pip5k; PIP5K3; Pipk5k3; PipkIII
UniProt ID: (Mouse) Q9Z1T6
Entrez Gene ID: (Mouse) 18711
nucleotide binding
1-phosphatidylinositol-3-phosphate 5-kinase activity
protein binding
ATP binding
zinc ion binding
kinase activity
phosphatidylinositol phosphate kinase activity
1-phosphatidylinositol-4-phosphate 5-kinase activity
transferase activity
metal ion binding
kinase
transferase
metabolite interconversion enzyme
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