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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • PIN1 Antibodies

          Invitrogen

          PIN1 Polyclonal Antibody

          View all (13) PIN1 antibodies
          Datasheet
          Protocols
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          Cite PIN1 Polyclonal Antibody

          Datasheet
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          • Antibody Testing Data (1)
          PIN1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          PIN1 Antibody (PA5-96057) in WB

          Western blot analysis of PIN1 in various lysates. Samples were incubated with PIN1 Polyclonal antibody (Product # PA5-96057) using a dilution of 1:2,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Product Details

          PA5-96057

          Applications
          Tested Dilution
          Publications

          免疫印迹 (WB)

          1:500-1:2,000
          -
          产品规格

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          分类

          Polyclonal

          类型

          Antibody

          Immunogen

          Recombinant fusion protein containing a sequence corresponding to amino acids 1-163 of human PIN1.
          View immunogen

          Conjugate

          Unconjugated

          形式

          Liquid

          浓度

          1.11 mg/mL

          纯化类型

          Affinity Chromatography

          保存液

          PBS, pH 7.3, with 50% glycerol

          内含物

          0.02% sodium azide

          保存条件

          -20° C, Avoid Freeze/Thaw Cycles

          RRID

          AB_2807859

          Product Specific Information

          Immunogen sequence: MADEEKLPPG WEKRMSRSSG RVYYFNHITN ASQWERPSGN SSSGGKNGQG EPARVRCSHL LVKHSQSRRP SSWRQEKITR TKEEALELIN GYIQKIKSGE EDFESLASQF SDCSSAKARG DLGAFSRGQM QKPFEDASFA LRTGEMSGPV FTDSGIHIIL RTE; Positive Samples: PC-3, 293T, HeLa, Mouse kidney, Rat brain, Rat heart, Mouse brain; Cellular Location: Cytoplasm, Nucleus, Nucleus speckle

          Target Information

          PIN1 (Peptidylprolyl Cis/Trans Isomerase, NIMA-Interacting 1) is a Protein Coding gene. Diseases associated with PIN1 include Meibomian Cyst and Viral Exanthem. Among its related pathways are Transport of the SLBP independent Mature mRNA and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include peptidyl-prolyl cis-trans isomerase activity and mitogen-activated protein kinase binding.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: EC 5.2.1.8; NIMA-interacting; Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; Peptidyl-prolyl cis-trans isomerase Pin1; PPIase Pin1; prolyl isomerase; protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1; Rotamase Pin1

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          Gene Aliases: 0610025L01Rik; D9Bwg1161e; DOD; PIN1; UBL5

          View more View less

          UniProt ID: (Human) Q13526, (Mouse) Q9QUR7

          View more View less

          Entrez Gene ID: (Human) 5300, (Mouse) 23988, (Rat) 298696

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          Molecular Function: chaperone

          Function(s)
          protein peptidyl-prolyl isomerization positive regulation of protein phosphorylation cell cycle regulation of mitotic nuclear division neuron differentiation negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of protein binding regulation of cytokinesis negative regulation of type I interferon production positive regulation of protein dephosphorylation negative regulation of protein catabolic process negative regulation of neuron apoptotic process positive regulation of neuron apoptotic process positive regulation of GTPase activity positive regulation of transcription from RNA polymerase II promoter synapse organization protein stabilization positive regulation of ubiquitin-protein transferase activity regulation of pathway-restricted SMAD protein phosphorylation positive regulation of cell growth involved in cardiac muscle cell development negative regulation of ERK1 and ERK2 cascade positive regulation of canonical Wnt signaling pathway regulation of protein localization to nucleus regulation of signal transduction by p53 class mediator negative regulation of cell motility regulation of cell proliferation
          Process(es)
          peptidyl-prolyl cis-trans isomerase activity motor activity protein binding beta-catenin binding mitogen-activated protein kinase kinase binding GTPase activating protein binding phosphoserine binding phosphothreonine binding isomerase activity
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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