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FIGURE: 1 / 1
PIN1 Antibody (PA5-96057) in WB
Western blot analysis of PIN1 in various lysates. Samples were incubated with PIN1 Polyclonal antibody (Product # PA5-96057) using a dilution of 1:2,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
Product Details
PA5-96057
产品规格
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-163 of human PIN1.
Conjugate
Unconjugated
形式
Liquid
浓度
1.11 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2807859
Product Specific Information
Immunogen sequence: MADEEKLPPG WEKRMSRSSG RVYYFNHITN ASQWERPSGN SSSGGKNGQG EPARVRCSHL LVKHSQSRRP SSWRQEKITR TKEEALELIN GYIQKIKSGE EDFESLASQF SDCSSAKARG DLGAFSRGQM QKPFEDASFA LRTGEMSGPV FTDSGIHIIL RTE; Positive Samples: PC-3, 293T, HeLa, Mouse kidney, Rat brain, Rat heart, Mouse brain; Cellular Location: Cytoplasm, Nucleus, Nucleus speckle
Target Information
PIN1 (Peptidylprolyl Cis/Trans Isomerase, NIMA-Interacting 1) is a Protein Coding gene. Diseases associated with PIN1 include Meibomian Cyst and Viral Exanthem. Among its related pathways are Transport of the SLBP independent Mature mRNA and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include peptidyl-prolyl cis-trans isomerase activity and mitogen-activated protein kinase binding.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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Bioinformatics
Protein Aliases: EC 5.2.1.8; NIMA-interacting; Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; Peptidyl-prolyl cis-trans isomerase Pin1; PPIase Pin1; prolyl isomerase; protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1; Rotamase Pin1
Gene Aliases: 0610025L01Rik; D9Bwg1161e; DOD; PIN1; UBL5
UniProt ID: (Human) Q13526, (Mouse) Q9QUR7
Entrez Gene ID: (Human) 5300, (Mouse) 23988, (Rat) 298696
Molecular Function:
chaperone
protein peptidyl-prolyl isomerization
positive regulation of protein phosphorylation
cell cycle
regulation of mitotic nuclear division
neuron differentiation
negative regulation of transforming growth factor beta receptor signaling pathway
negative regulation of protein binding
regulation of cytokinesis
negative regulation of type I interferon production
positive regulation of protein dephosphorylation
negative regulation of protein catabolic process
negative regulation of neuron apoptotic process
positive regulation of neuron apoptotic process
positive regulation of GTPase activity
positive regulation of transcription from RNA polymerase II promoter
synapse organization
protein stabilization
positive regulation of ubiquitin-protein transferase activity
regulation of pathway-restricted SMAD protein phosphorylation
positive regulation of cell growth involved in cardiac muscle cell development
negative regulation of ERK1 and ERK2 cascade
positive regulation of canonical Wnt signaling pathway
regulation of protein localization to nucleus
regulation of signal transduction by p53 class mediator
negative regulation of cell motility
regulation of cell proliferation
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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