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Proteintech
PIP4K2A Polyclonal Antibody
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产品信息
12469-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PIP4K2A Fusion Protein Ag3152 (59-406 aa encoded by BC018034)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: VMLMPDDFK AYSKIKVDNH LFNKENMPSH FKFKEYCPMV FRNLRERFGI DDQDFQNSLT RSAPLPNDSQ ARSGARFHTS YDKRYIIKTI TSEDVAEMHN ILKKYHQYIV ECHGITLLPQ FLGMYRLNVD GVEIYVIVTR NVFSHRLSVY RKYDLKGSTV AREASDKEKA KELPTLKDND FINEGQKIYI DDNNKKVFLE KLKKDVEFLA QLKLMDYSLL VGIHDVERAE QEEVECEEND GEEEGESDGT HPVGTPPDSP GNTLNSSPPL APGEFDPNID VYGIKCHENS PRKEVYFMAI IDILTHYDAK KKAAHAAKTV KHGAGAEIST VNPEQYSKRF LDFIGHILT (59-406 aa encoded by BC018034)
靶标信息
PIP4K2A lipid kinase or phosphatidylinositol-5-phosphate 4-kinase, type II, alpha, is a member of the phosphatidylinositol-5-phosphate 4-kinase family that catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-4,5-bisphosphate. PIP4K2A plays as essential role in the phosphoinositide signal transduction cascades as the precursor to second messengers and is involved in the regulation of secretion, cell proliferation, differentiation, and motility. PIP4K2A may be one of the factors related to the regulation of the beta-globin gene expression and the different levels of Hb H in alpha-thalassemic patients. Diseases associated with PIP4K2A include B-Lymphoblastic Leukemia/Lymphoma With Hyperdiploidy and Bipolar Disorder.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha; 1-phosphatidylinositol-4-phosphate kinase; 1-phosphatidylinositol-4-phosphate-5-kinase; 1-phosphatidylinositol-5-phosphate 4-kinase 2-alpha; 1-phosphatidylinositol-5-phosphate 4-kinase A; Diphosphoinositide kinase 2-alpha; Phosphatidylinositol 5-Phosphate 4-Kinase; Phosphatidylinositol 5-phosphate 4-kinase type II alpha; Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha; phosphatidylinositol-4-phosphate 5-kinase, type II, alpha; phosphatidylinositol-5-phosphate 4-kinase type-2 alpha; phosphatidylinositol-5-phosphate 4-kinase, type II, alpha; PI(5)P 4-kinase type II alpha; PI5P4Kalpha; PIP4KII-alpha; PIP5KIIalpha; PIP5KIII; PIPK2 alpha; PtdIns(4)P-5-kinase B isoform; PtdIns(4)P-5-kinase C isoform; PtdIns(5)P-4-kinase isoform 2-alpha; type II phosphatidylinositol-4-phosphate 5-kinase 53 K isoform
基因别名: AW742916; PI5P4KA; PIP4K2A; Pip4ka; PIP5K2; PIP5K2A; PIP5KII-alpha; PIP5KIIA; PIPK
UniProt ID: (Human) P48426, (Mouse) O70172, (Rat) Q9R0I8
Entrez Gene ID: (Human) 5305, (Mouse) 18718, (Rat) 116723
