Proteintech

PIP5K1A Polyclonal Antibody

Name: PIP5K1A Polyclonal Antibody
Brand: Proteintech
SKU: 15713-1-AP

18 篇参考文献

查看其他11个PIP5K1A抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (10)

PIP5K1A Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 10

PIP5K1A Antibody (15713-1-AP) in ICC/IF

Immunofluorescent analysis of Hela cells, using PIP5K1A antibody 15713-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

PIP5K1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PIP5K1A Antibody in Flow Cytometry (Flow)

PIP5K1A Antibody in Immunoprecipitation (IP)

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Immunogen image

Immunogen Image PIP5K1A Polyclonal Antibody

产品信息

15713-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

查看9篇已发表文章 9篇已发表文章

免疫组化 (IHC)

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免疫组化（石蜡） (IHC (P))

1:50-1:500

免疫细胞化学 (ICC/IF)

1:10-1:100

查看5篇已发表文章 5篇已发表文章

流式细胞分析 (Flow)

0.5 µg/1x10^6 cells

免疫沉淀 (IP)

0.5-4.0 µg

查看2篇已发表文章 2篇已发表文章

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

PIP5K1A Fusion Protein Ag8340 (151-500 aa encoded by BC007833)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.22 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: SLCSEPLIE LCSSGASGSL FYVSSDDEFI IKTVQHKEAE FLQKLLPGYY MNLNQNPRTL LPKFYGLYCV QAGGKNIRIV VMNNLLPRSV KMHIKYDLKG STYKRRASQK EREKPLPTFK DLDFLQDIPD GLFLDADMYN ALCKTLQRDC LVLQSFKIMD YSLLMSIHNI DHAQREPLSS ETQYSVDTRR PAPQKALYST AMESIQGEAR RGGTMETDDH MGGIPARNSK GERLLLYIGI IDILQSYRFV KKLEHSWKAL VHDGDTVSVH RPGFYAERFQ RFMCNTVFKK IPCVHLGRPD VLPQTPPLEE ISEGSPIPDP SFSPLVGETL QMLTTSTTLE KLEVAESEFT H (151-500 aa encoded by BC007833)

靶标信息

PIP5K1A lipid kinase or phosphatidylinositol-4-phosphate 5-kinase 1 alpha phosphorylates phosphatidylinositol-4-phosphate to form phosphatidylinositol 4,5-bisphosphate. PIP5K1 is required for Wnt3a-induced LRP6 phosphorylation at ser1490 in mammalian cells. Wnt3a stimulates the formation of phosphatidylinositol 4,5-bisphosphates through 'frizzled' and 'disheveled', the latter of which directly interacts with and activated PIP5KI. PIP5K1A-mediated PIP(2) production is crucial for HIV-1 entry and the early steps of infection in permissive lymphocytes. Overexpression of wild-type PI4P5K1A increases HIV-1 Env-mediated PIP(2) production and enhances viral replication in primary lymphocytes.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: 68 kDa type I phosphatidylinositol 4-phosphate 5-kinase; 68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha; 68 kDa type I phosphatidylinositol-4-phosphate 5-kinase; 68 kDa type I phosphatidylinositol-4-phosphate 5-kinase alpha; Phosphatidylinositol 4-phosphate 5-kinase type I alpha; Phosphatidylinositol 4-phosphate 5-kinase type I beta; Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha; phosphatidylinositol-4-phosphate 5-kinase; phosphatidylinositol-4-phosphate 5-kinase type I alpha; phosphatidylinositol-4-phosphate 5-kinase type-1 alpha; phosphatidylinositol-4-phosphate 5-kinase, type 1 beta; phosphatidylinositol-4-phosphate 5-kinase, type I, alpha; PI4P5KIbeta; PI51A; PIP5K1-alpha; PIP5KIalpha; ptdIns(4)P-5-kinase 1 alpha

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基因别名: PI4P5K-I[a]; PIP5K1-alpha; PIP5K1A; Pip5k1b; PIP5KIalpha; Pipk5a

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UniProt ID: (Human) Q99755, (Mouse) P70182

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Entrez Gene ID: (Human) 8394, (Mouse) 18720, (Rat) 365865

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功能