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Invitrogen
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Immunogen sequence: SRTSHREAMS LKGHLQSVTA PMGITMKPAE MIEVDGDANS YIDTLRKYTR PTLQMVICIL PNDDKRRYDS I
Highest antigen sequence identity to the following orthologs: Mouse - 39%, Rat - 39%.
PIWI-L3 is a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that are crucial for the biogenesis and function of small non-coding RNAs and play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. Recent studies have shown that overexpression of PIWI-L3 (as well as other PIWI-like proteins) are potential biomarkers for astrocytic glioma, meningioma, and other cancers.
仅用于科研。不用于诊断过程。未经明确授权不得转售。