Invitrogen

PJA2 Polyclonal Antibody

Name: PJA2 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-59142

高级验证

查看其他8个PJA2抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (4)
高级验证 (1)

PJA2 Antibody in Immunocytochemistry (ICC/IF)

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PJA2 Antibody (PA5-59142) in ICC/IF

Immunofluorecent analysis of PJA2 in human cell line U-2 OS using PJA2 Polyclonal Antibody (Product # PA5-59142). Staining shows localization to intermediate filaments.

PJA2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PJA2 Antibody in Immunohistochemistry (IHC)

Product Image Gallery

PJA2 Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of PJA2 demonstrates antibody specificity. Immunohistochemical analysis of PJA2 using anti-PJA2 Polyclonal Antibody (Product # PA5-59142), shows significant staining of PJA2 in human cerebral cortex and shows minimal or weak staining in human skeletal muscle tissues. The relative expression levels of PJA2 within each tissue is shown using RNA-Seq. {RE}

Immunogen image

Immunogen Image PJA2 Polyclonal Antibody

产品信息

PA5-59142

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:200-1:500

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human PJA2. Recombinant protein control fragment (Product #RP-96982).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2645592

产品详细信息

Immunogen sequence: GIALVHTDSY DPDGKHGEDN DHLQLSAEVV EGSRYQESLG NTVFELENRE AEAYTGLSPP VPSFNCEVRD EFEELDSVPL VKSSAGDTEF VH

Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 64%.

靶标信息

Has E2-dependent E3 ubiquitin-protein ligase activity. Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation. Essential for PKA-mediated long-term memory processes.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: E3 ubiquitin-protein ligase Praja-2; praja 2, RING-H2 motif containing; praja ring finger 2, E3 ubiquitin protein ligase; Praja2; RING finger protein 131; RING-type E3 ubiquitin transferase Praja-2

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基因别名: KIAA0438; Neurodap1; PJA2; RNF131

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UniProt ID: (Human) O43164

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Entrez Gene ID: (Human) 9867

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功能

ubiquitin-protein transferase activity zinc ion binding ligase activity protein kinase A catalytic subunit binding protein kinase A regulatory subunit binding ubiquitin protein ligase activity ubiquitin-protein ligase

参与通路

long-term memory regulation of protein kinase A signaling protein ubiquitination hippo signaling