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Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
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Positive Control: 293T, A431, HeLa, HepG2
Predicted Reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Pig (100%), Rabbit (100%), Bovine (100%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The PKC family of serine/threonine kinases, including PRKCZ (PKC zeta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent. PKC zeta plays a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: atypical protein kinase C; kinase nPKC-zeta; KPCZ; nPKC-zeta; nPKC-zeta PRKCZ; protein kinase C zeta subspecies; Protein kinase C zeta type; protein kinase C, zeta
基因别名: AI098070; aPKCzeta; C80388; nPKC-zeta; PKC-ZETA; PKC2; Pkcz; PRKCZ; R74924; zetaPKC
UniProt ID: (Human) Q05513, (Mouse) Q02956
Entrez Gene ID: (Human) 5590, (Mouse) 18762