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Invitrogen
PLAGL2 Polyclonal Antibody
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产品信息
PA5-52222
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human PLAGL2
偶联物
形式
Liquid
浓度
0.1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: RHVKKSHSQE LLKIKTEPVD MLGLLSCSST VSVKEELSPV LCMASRDVMG TKAFPGMLPM GMYGAHIPTM PSTGVPHSLV HNTLPMGMSY PLESSPISSP AQLPPKYQL
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%.
靶标信息
The PLAG (Pleiomorphic adenoma gene) family of zinc finger proteins include PLAG1, ZAC1 and PLAG-like 2 (PLAGL2). PLAG1 is the target gene for the pleiomorphic adenomas of the salivary gland. ZAC1 (PLAGL1) concomitantly controls apoptosis and cell cycle arrest through separate pathways. ZAC1 also acts as a transcriptional cofactor for nuclear receptors. PLAGL2 belongs to the krueppel C2H2-type zinc-finger protein family and contains 6 C2H2-type zinc fingers. It functions as a positive regulator of transcription and localizes to the nucleus. PLAGL2 is ubiquitously expressed with particular abundance in spleen, lung and testis, where it may be involved in cell cycle arrest and apoptosis of tumor cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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