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Proteintech
PLEK Polyclonal Antibody
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产品信息
12506-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PLEK Fusion Protein Ag3187 (1-350 aa encoded by BC018549)
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MEPKRIREG YLVKKGSVFN TWKPMWVVLL EDGIEFYKKK SDNSPKGMIP LKGSTLTSPC QDFGKRMFVF KITTTKQQDH FFQAAFLEER DAWVRDIKKA IKCIEGGQKF ARKSTRRSIR LPETIDLGAL YLSMKDTEKG IKELNLEKDK KIFNHCFTGN CVIDWLVSNQ SVRNRQEGLM IASSLLNEGY LQPAGDMSKS AVDGTAENPF LDNPDAFYYF PDSGFFCEEN SSDDDVILKE EFRGVIIKQG CLLKQGHRRK NWKVRKFILR EDPAYLHYYD PAGAEDPLGA IHLRGCVVTS VESNSNGRKS EEENLFEIIT ADEVHYFLQA ATPKERTEWI KAIQMASRTG K (1-350 aa encoded by BC018549)
靶标信息
Major protein kinase C substrate of platelets.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: FLJ27168; p47; Platelet 47 kDa protein; Pleckstrin
基因别名: 2010300B13Rik; P47; PLEK
UniProt ID: (Human) P08567, (Mouse) Q9JHK5, (Rat) Q4KM33
Entrez Gene ID: (Human) 5341, (Mouse) 56193, (Rat) 364206
hematopoietic progenitor cell differentiation
platelet degranulation
vesicle docking involved in exocytosis
integrin-mediated signaling pathway
positive regulation of platelet activation
negative regulation of inositol phosphate biosynthetic process
positive regulation of inositol-polyphosphate 5-phosphatase activity
cell projection organization
positive regulation of actin filament depolymerization
phospholipase C-inhibiting G-protein coupled receptor signaling pathway
cortical actin cytoskeleton organization
ruffle organization
actin cytoskeleton reorganization
positive regulation of actin filament bundle assembly
positive regulation of integrin activation
negative regulation of G-protein coupled receptor protein signaling pathway
phosphatidylinositol metabolic process
negative regulation of calcium-mediated signaling
regulation of cell diameter
thrombin receptor signaling pathway
platelet aggregation
protein kinase C signaling
protein secretion by platelet
intracellular signal transduction
