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Proteintech
PLEKHA8 Polyclonal Antibody
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产品信息
15410-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PLEKHA8 Fusion Protein Ag7677 (1-350 aa encoded by BC002838)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MEGVLYKWT NYLSGWQPRW FLLCGGILSY YDSPEDAWKG CKGSIQMAVC EIQVHSVDNT RMDLIIPGEQ YFYLKARSVA ERQRWLVALG SAKACLTDSR TQKEKEFAEN TENLKTKMSE LRLYCDLLVQ QVDKTKEVTT TGVSNSEEGI DVGTLLKSTC NTFLKTLEEC MQIANAAFTS ELLYRTPPGS PQLAMLKSSK MKHPIIPIHN SLERQMELST CENGSLNMEI NGEEEILMKN KNSLYLKSAE IDCSISSEEN TDDNITVQGE IRKEDGMENL KNHDNNLTQS GSDSSCSPEC LWEEGKEVIP TFFSTMNTSF SDIELLEDSG IPTEAFLASC YAVVPVLDKL G (1-350 aa encoded by BC002838)
靶标信息
Cargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans-Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: FAPP-2; hFAPP2; MGC3358; PH domain-containing family A member 8; Phosphatidylinositol-four-phosphate adapter protein 2; phosphoinositol 4-phosphate adapter protein 2; pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8; Pleckstrin homology domain-containing family A member 8; Serologically defined breast cancer antigen NY-BR-86
基因别名: 6330400G01; AA517676; BC052360; FAPP-2; FAPP2; PLEKHA8; RGD1563940
UniProt ID: (Human) Q96JA3, (Mouse) Q80W71, (Rat) D3ZY60
Entrez Gene ID: (Human) 84725, (Mouse) 231999, (Rat) 500132
