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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: KGDRKSTGLK LSKKKARRRH TDDPSKECFT LKFDLNVDIE TEIVPAMKKK SLGEVLLPVF ERKGIALGKV DIYLDQSNTP LSL
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
Guanine nucleotide exchange factor that activates RHOA and maybe the NF-kappa-B signaling pathway. Involved in the control of neuronal cell differentiation. Plays a role in angiogenesis through regulation of endothelial cells chemotaxis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: guanine nucleotide exchange factor 720; NFkB activating protein; novel PH domain-containing protein; PH domain-containing family G member 5; pleckstrin homology domain containing, family G (with RhoGef domain) member 5; synectin-binding guanine exchange factor; unnamed protein product
基因别名: ARHGEF45; CMTRIC; DSMA4; GEF720; HMNR4; Syx; Tech
UniProt ID: (Human) O94827
Entrez Gene ID: (Human) 57449