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Proteintech
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28154-1-AP detects the isoforms of PLEKHH3 protein around 80-85 kDa in SDS-PAGE.
Immunogen sequence: YGVSAPGPG YAPLREEAVR LFLALQALEG ARRPGPLMQG VLQTCRDLPA LRDELFLQLA KQTSGPAGPP GLPATQDPAA LRYWQLLTCM SCTFRPGGAV RGHLLGHLER TEQALPDSEL AEYARFIRKA LGRTRGRELV PSLAEISALS QRQEL (251-404 aa encoded by BC052978)
PLEKHH3, a gene related to endothelial tight junction, is associated with obstructive sleep apnea (OSA) and angiogenesis. It has been reported that the expression of PLEKHH3 protein was increased in the OSA patients. PLEKHH3 may play a key role in OSA and angiogenesis by specifically regulating the endothelial cells formation of tight junctions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: PH domain-containing family H member 3; pleckstrin homology domain containing, family H (with MyTH4 domain) member 3; Pleckstrin homology domain-containing family H member 3
基因别名: BC020025; PLEKHH3
UniProt ID: (Human) Q7Z736, (Mouse) Q8VCE9
Entrez Gene ID: (Human) 79990, (Mouse) 217198