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Rockland
PLEKHM2 Polyclonal Antibody
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PLEKHM2 Antibody (600-401-DQ6) in ICC/IF
Immunofluorescence Microscopy of PLEKHM2 antibody. Tissue: Human brain cells. Fixation: 0.5% PFA. Antigen retrieval: not required. Primary antibody: PLEKHM2 antibody at 20 µg/mL for 1 hr at RT. Secondary antibody: Fluorescein rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: PLEKHM2 is cytoplasmic. Staining: PLEKHM2 as red fluorescent signal.
产品信息
600-401-DQ6
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Anti-PLEKHM2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide from near the C-terminus of human PLEKHM2.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: novel RUN and PH domain-containing protein; PH domain-containing family M member 2; pleckstrin homology domain containing, family M (with RUN domain) member 2; Pleckstrin homology domain-containing family M member 2; RP11-169K16.1; Salmonella-induced filaments A and kinesin-interacting protein; SifA (Salmonella-induced filaments A) and kinesin-interacting protein; SifA and kinesin-interacting protein
基因别名: 2310034J19Rik; AI854247; KIAA0842; mKIAA0842; PLEKHM2; SKIP
UniProt ID: (Human) Q8IWE5, (Mouse) Q80TQ5
Entrez Gene ID: (Human) 23207, (Mouse) 69582, (Rat) 313667
