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Invitrogen
PLM Polyclonal Antibody
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产品信息
PA5-79288
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived human FXYD1 recombinant protein (Position: E21-R92).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Liver Tissue, Rat Cardiac Muscle Tissue, Mouse Cardiac Muscle Tissue, HEPG2 whole cell, HELA whole cell. IHC: mouse cardiac muscle tissue, rat cardiac muscle tissue, human prostatic cancer tissue.
靶标信息
This gene encodes a member of the FXYD family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity and act as an accessory protein of Na,K-ATPase. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FXYD domain-containing ion transport regulator 1; Phospholemman; Sodium Potassium ATPase; Sodium/potassium-transporting ATPase subunit FXYD1
基因别名: 0610012C17Rik; 1110006M24Rik; FXYD1; PLM; Pml
UniProt ID: (Human) O00168, (Mouse) Q9Z239, (Rat) O08589
Entrez Gene ID: (Human) 5348, (Mouse) 56188, (Rat) 58971
chloride transport
muscle contraction
regulation of heart contraction
ion transmembrane transport
regulation of cardiac muscle cell membrane potential
chloride transmembrane transport
positive regulation of sodium ion export from cell
regulation of cardiac conduction
regulation of sodium ion transmembrane transporter activity
transport
ion transport
positive regulation of organic acid transport
regulation of cytosolic calcium ion concentration
regulation of cardiac muscle cell contraction
positive regulation of inorganic anion transmembrane transport
brain development
