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Invitrogen
PLXNB3 Polyclonal Antibody
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PLXNB3 Antibody (PA5-47882) in IHC (F)
Immunohistochemical analysis of PLXNB3 in perfusion fixed frozen sections of mouse brain. Samples were incubated in PLXNB3 polyclonal antibody (Product # PA5-47882) using a dilution of 1.7 µg/mL overnight at 4 °C followed by NorthernLights™ 557-conjugated Anti-Sheep IgG Secondary Antibody (red) and counterstained with DAPI (blue). Specific staining was localized to oligodendrocytes.
产品信息
PA5-47882
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Sheep
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CHO-derived recombinant mouse Plexin B3 His25-Gln1235
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
In direct ELISAs, approximately 38% cross-reactivity with recombinant human (rh) Plexin B3 is observed, and less than 1% cross-reactivity with rhPlexin B2 is observed.
Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
靶标信息
The protein encoded by this gene is a member of the plexin family. It functions as a receptor for semaphorin 5A, and plays a role in axon guidance, invasive growth and cell migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ76953; plexin 6; Plexin-6; Plexin-B3; plexin-B3 {ECO:0000303|PubMed:20696765}; plxnb3 {ECO:0000312|Ensembl:ENSRNOP00000053235}; Protein Plxnb3
基因别名: AI451018; Kiaa1206; Plxn6; Plxnb3; RGD1560615
UniProt ID: (Mouse) Q9QY40, (Rat) D3ZLH5
Entrez Gene ID: (Mouse) 140571, (Rat) 363517
positive regulation of endothelial cell proliferation
negative regulation of cell adhesion
signal transduction
nervous system development
negative regulation of lamellipodium assembly
negative regulation of cell migration
negative regulation of GTPase activity
positive chemotaxis
cell chemotaxis
semaphorin-plexin signaling pathway
