Invitrogen

PLZF Monoclonal Antibody (816416)

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问题与答案

抗体检测数据 (1)

PLZF Antibody in Western Blot (WB)

PLZF Antibody in Western Blot (WB)

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PLZF Antibody (MA5-61945) in WB

Western Blot analysis of PLZF in BaF3 and KG-1 using PLZF monoclonal antibody (Product # MA5-61945).

PLZF Antibody in Western Blot (WB)

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PLZF Antibody in Western Blot (WB) — Western Blot analysis of PLZF in BaF3 and KG-1 using PLZF monoclonal antibody (Product # MA5-61945).

产品信息

MA5-61945

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1 µg/mL

-

产品规格

种属反应

Mouse

宿主/亚型

Rat / IgG1

分类

Monoclonal

类型

Antibody

克隆号

816416

抗原

E. coli-derived recombinant mouse PLZF, Met1-Gln254

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.5 mg/mL

纯化类型

Protein A/G

保存液

PBS with trehalose

内含物

no preservative

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitute at 0.5 mg/mL in sterile PBS.

靶标信息

This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Green's luxoid; luxoid; zinc finger and BTB domain-containing protein 16; zinc finger protein 145

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基因别名: AI467657; lu; PLZF; Zfp145

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Entrez Gene ID: (Mouse) 235320

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RNA polymerase II distal enhancer sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding DNA binding double-stranded DNA binding transcription factor activity, sequence-specific DNA binding protein binding protein C-terminus binding protein domain specific binding identical protein binding protein homodimerization activity C2H2 zinc finger transcription factor

negative regulation of transcription from RNA polymerase II promoter skeletal system development mesonephros development regulation of transcription, DNA-templated transcription from RNA polymerase II promoter central nervous system development negative regulation of cell proliferation embryonic pattern specification anterior/posterior pattern specification hemopoiesis embryonic limb morphogenesis positive regulation of chondrocyte differentiation protein localization to nucleus embryonic hindlimb morphogenesis forelimb morphogenesis hindlimb morphogenesis embryonic digit morphogenesis positive regulation of apoptotic process positive regulation of fat cell differentiation negative regulation of myeloid cell differentiation positive regulation of ossification negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated male germ-line stem cell asymmetric division positive regulation of NK T cell differentiation cartilage development positive regulation of cartilage development