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Peptide sequence: EEEELNDSSL DLGPTADYVF PDLTEKAGSI EDTSQAQELP NLPSPLPKMN
Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Podolyxin is a CD34 family member expressed by podocytes, vascular endothelium, mesothelium, and a subset of hematopoietic progenitors. It is the major sialoprotein in the glycocalyx of glomerular podocytes. The physiologic role of podolyxin in leukemic blasts is unknown. However, it is thought of as a candidate prostate cancer tumor aggressiveness gene. Podolyxin appears to complement CD34 as a useful cell surface marker for hemangioblasts, the common precursors of hematopoietic and endothelial cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
Protein Aliases: Endoglycan; podocalyxin-like 2; Podocalyxin-like protein 2
Gene Aliases: EG; PODLX2; PODXL2; UNQ1861/PRO3742
UniProt ID: (Human) Q9NZ53
Entrez Gene ID: (Human) 50512
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