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Invitrogen
POLK Polyclonal Antibody
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POLK Antibody (PA5-64942)
Relative expression in western blot: Antibody specificity was demonstrated by detection of known differential basal expression of the target across tissue/cell models. Expression of POLK was observed specifically in A-549 cells and in MCF-7 cells using anti-POLK Polyclonal Antibody (Product # PA5-64942) in western blot. The relative expression levels of POLK within each cell line is shown using RNA-Seq. {RE... View More
产品信息
PA5-64942
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human POLK
偶联物
形式
Liquid
浓度
0.3 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: AMPGFIAKRLC PQLIIVPPNF DKYRAVSKEV KEILADYDPN FMAMSLDEAY LNITKHLEER QNWPEDKRRY FIKMGSSVEN DNPGKEVNKL SEHERSISPL LFEESPSDVQ PPGDPFQVNF EEQNNPQILQ NS
Highest antigen sequence identity to the following orthologs - mouse 82%, rat 80%.
靶标信息
External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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