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Invitrogen
POLK Polyclonal Antibody
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
产品信息
PA5-64942
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
0.04-0.4 µg/mL | - |
免疫细胞化学 (ICC/IF) |
0.25-2 µg/mL | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant Human POLK |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.3 mg/mL |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2665056 |
产品详细信息
Immunogen sequence: AMPGFIAKRLC PQLIIVPPNF DKYRAVSKEV KEILADYDPN FMAMSLDEAY LNITKHLEER QNWPEDKRRY FIKMGSSVEN DNPGKEVNKL SEHERSISPL LFEESPSDVQ PPGDPFQVNF EEQNNPQILQ NS
Highest antigen sequence identity to the following orthologs - mouse 82%, rat 80%.
靶标信息
External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DINB protein; DINP; DNA polymerase kappa; polymerase (DNA directed) kappa
基因别名: DINB1; POLK
