Proteintech

POLR1E Polyclonal Antibody

Name: POLR1E Polyclonal Antibody
Brand: Proteintech
SKU: 16145-1-AP

6 篇参考文献

查看其他8个POLR1E抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (5)

POLR1E Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 5

POLR1E Antibody (16145-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using 16145-1-AP ( POLR1E Antibody) at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

POLR1E Antibody in Immunoprecipitation (IP)

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Immunogen image

Immunogen Image POLR1E Polyclonal Antibody

产品信息

16145-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:4,000

查看3篇已发表文章 3篇已发表文章

免疫组化（石蜡） (IHC (P))

1:20-1:200

免疫细胞化学 (ICC/IF)

查看2篇已发表文章 2篇已发表文章

免疫沉淀 (IP)

0.5-4.0 µg

染色质免疫沉淀实验 (ChIP)

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

POLR1E Fusion Protein Ag9269 (104-419 aa encoded by BC014331)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.23 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: AELFNMQPL FSDVSVESEL ALESQTKTYR EKMDSCIEAF GTTKQKRALN TRRMNRVGNE SLNRAVAKAA ETIIDTKGVT ALVSDAIHND LQDDSLYLPP CYDDAAKPED VYKFEDLLSP AEYEALQSPS EAFRNVTSEE ILKMIEENSH CTFVIEALKS LPSDVESRDR QARCIWFLDT LIKFRAHRVV KRKSALGPGV PHIINTKLLK HFTCLTYNNG RLRNLISDSM KAKITAYVII LALHIHDFQI DLTVLQRDLK LSEKRMMEIA KAMRLKISKR KVSVAAGSEE DHKLGTLSLP LPPAQTSDRL AKRRKIT (104-419 aa encoded by BC014331 )

靶标信息

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors (PubMed:24207024). Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF (PubMed:24207024). [UniProt]

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: DNA-directed RNA polymerase I subunit E; DNA-directed RNA polymerase I subunit RPA49; FLJ13390; FLJ13970; polymerase (RNA) I associated factor 1; polymerase (RNA) I polypeptide E; polymerase (RNA) I polypeptide E, 53kDa; polymerase (RNA) I subunit E; RNA polymerase I associated factor (Paf53); RNA polymerase I subunit A49; RNA polymerase I-associated factor 1; RNA polymerase I-associated factor 53; RP11-405L18.3

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基因别名: 53kDa; AU042259; D030019D19Rik; PAF53; POLR1E; PRAF1; RGD1565773

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UniProt ID: (Human) Q9GZS1, (Mouse) Q8K202

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Entrez Gene ID: (Human) 64425, (Mouse) 64424, (Rat) 313245

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功能

RNA polymerase I activity RNA polymerase I transcription factor binding DNA binding DNA-directed RNA polymerase activity protein binding molecular_function DNA-directed RNA polymerase RNA metabolism protein nucleic acid metabolism protein

参与通路

RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript transcription initiation from RNA polymerase I promoter transcription elongation from RNA polymerase I promoter termination of RNA polymerase I transcription rRNA transcription positive regulation of gene expression, epigenetic transcription, DNA-templated biological_process