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Proteintech
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Immunogen sequence: VTMVSPSTA GGPAQKLQGN GVAGSPSVVP AAVVSAAHIQ TSPQAKVLLH MTGQMTVNQA RNAVRTVAAH NQERPTAAVT PIQVQNAAGL SPASVGLSHH SLASPQPAPL MPGSATHTAA ISISRASAPL ACAAAAPLTS PSITSASLEA EPSGRIVTVL PGLPTSPDSA SSACGNSSAT KPDKDSKKEK KGLLKLLSGA STKRKPRVSP PASPTLEVEL GSAELPLQGA VGPELPPGGG HGRAGSCPVD GDGPVTTAVA GAALAQDAFH RKASSLDSAV PIAPPPRQAC SSLGPVLNES RPVVCERHRV VVSYPPQSEA ELELKEGDIV FVHKKREDGW FKGTLQRNGK TGLFPGSFVE NI (696-1056 aa encoded by BC053671)
This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: E3 ubiquitin-protein ligase SH3RF1; FLJ21602; plenty of SH3 domains; Plenty of SH3s; Protein POSH; putative E3 ubiquitin-protein ligase SH3RF1; putative scaffolding protein POSH; RING finger protein 142; RING-type E3 ubiquitin transferase SH3RF1; SH3 domain-containing RING finger protein 1; SH3 multiple domains 2; SH3 multiple domains protein 2
基因别名: 2200003J05Rik; KIAA1494; POSH; POSH1; R75531; RNF142; SH3MD2; SH3RF1
UniProt ID: (Human) Q7Z6J0, (Rat) Q71F54, (Mouse) Q69ZI1
Entrez Gene ID: (Human) 57630, (Rat) 306417, (Mouse) 59009