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OriGene
POU4F3 Monoclonal Antibody (OTI6H9), TrueMAB™
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图: 1 / 1
POU4F3 Antibody (CF808755) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY POU4F3 (RC21120°C, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-POU4F. Positive lysates LY400949 (100 µg) and LC400949 (20 µg) can be purchased separately from OriGene.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
CF808755
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI6H9
抗原
Human recombinant protein fragment corresponding to amino acids 179-338 of human POU4F3 produced in E.coli.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
POU4F3 encodes a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. This protein is found in the retina and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in this gene are the cause of non-syndromic sensorineural deafness autosomal dominant type 15.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: brain-3C; brain-specific homeobox POU domain protein 3C; brain-specific homeobox/POU domain protein 3C; brn-3C; deafness, autosomal dominant 42; MGC138412
基因别名: Brn3.1; BRN3C; ddl; DFNA15; DFNA42; DFNA52; dreidel
UniProt ID: (Human) Q15319, (Mouse) Q63955, (Rat) D3ZTL1
Entrez Gene ID: (Human) 5459, (Mouse) 18998, (Rat) 364855
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
apoptotic process
sensory perception of sound
vestibulocochlear nerve development
retinal ganglion cell axon guidance
inner ear morphogenesis
auditory receptor cell differentiation
positive regulation of transcription from RNA polymerase II promoter
axon extension
inner ear development
neuromuscular process controlling balance
neuron apoptotic process
inner ear receptor cell differentiation
visual perception
spermatogenesis
biological_process
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