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Invitrogen
POU6F2 Polyclonal Antibody
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产品信息
PA5-52590
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human POU6F2
偶联物
形式
Liquid
浓度
0.2 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: LRGEDKAATS DSELNEPLLA PVESNDSEDT PSKLFGARGN PALSDPGTPD QHQASQTHPP FPVGPQPLLT AQQLASAVAG VMPGGPPALN QPILIPFNMA GQLGGQQGLV LTLPTANLTN IQGLVAAAAA GGIMTLPLQN LQAT
Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 26%.
靶标信息
This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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