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产品信息
PA5-17825
产品规格
种属反应
Fruit fly,
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to the amino-terminal sequence of human PP1alpha
偶联物
Unconjugated
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
内含物
no preservative
保存条件
-20°C
RRID
AB_10986813
产品详细信息
It is not recommended to aliquot this antibody.
This antibody is not cross-reactive with PP1-delta or PP1-gamma.
靶标信息
This gene encodes a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum. The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CG6593-PA; CG6593-PB; GADD34; LD14639p; MGC15877; MGC1674; PP-1A; Pp1alpha-96A-PA; Pp1alpha-96A-PB; protein phosphatase 1; protein phosphatase 1, catalytic subunit, alpha isoform; protein phosphatase 1, catalytic subunit, alpha isozyme; Protein phosphatase type 1 alpha, catalytic subunit; protein phosphatase-1d; serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit; Serine/threonine-protein phosphatase alpha-1 isoform; Serine/threonine-protein phosphatase PP1-alpha catalytic subunit; testicular tissue protein Li 155
基因别名: 96A; CG6593; dism2; Dmel\CG6593; Dmel_CG6593; DmPp1-96A; PP-1A; PP1; PP1 96A; PP1 alpha96a; Pp1-96A; PP1A; PP1A-96A; PP1alpha; PP1alpha-96A; PP1alpha96A; PP1alpha[[1]]; PP1c; PP1c 96A; PPP1A; Ppp1c; PPP1CA
UniProt ID: (Human) P62136, (Fruit fly) P48461, (Mouse) P62137, (Rat) P62138
Entrez Gene ID: (Human) 5499, (Fruit fly) 42922, (Mouse) 19045, (Rat) 24668
分子生物学功能:
protein phosphatase
glycogen metabolic process
regulation of glycogen biosynthetic process
regulation of glycogen catabolic process
protein dephosphorylation
cell cycle
dephosphorylation
lung development
negative regulation of protein binding
circadian regulation of gene expression
regulation of translational initiation by eIF2 alpha dephosphorylation
regulation of circadian rhythm
entrainment of circadian clock by photoperiod
branching morphogenesis of an epithelial tube
cell division
regulation of canonical Wnt signaling pathway
beta-catenin destruction complex disassembly
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of innate immune response
negative regulation of smoothened signaling pathway
defense response to Gram-negative bacterium
positive regulation of canonical Wnt signaling pathway
carbohydrate metabolic process
regulation of translation
female meiotic division
cellular process
rhythmic process
