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Invitrogen
PP1 alpha Monoclonal Antibody (5E9)
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产品信息
MA5-17155
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
5E9
抗原
Purified recombinant fragment of human PPP1CA expressed in E. Coli.
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存液
ascites
内含物
0.03% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA5-17155 targets PPP1CA in indirect ELISA and WB applications and shows reactivity with Human samples.
The MA5-17155 immunogen is purified recombinant fragment of human PPP1CA expressed in E. Coli.
MA5-17155 detects PPP1CA which has a predicted molecular weight of approximately 38kDa.
靶标信息
This gene encodes a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum. The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GADD34; MGC15877; MGC1674; PP-1A; protein phosphatase 1, catalytic subunit, alpha isoform; protein phosphatase 1, catalytic subunit, alpha isozyme; serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit; Serine/threonine-protein phosphatase PP1-alpha catalytic subunit; testicular tissue protein Li 155
基因别名: PP-1A; PP1A; PP1alpha; PPP1A; PPP1CA
UniProt ID: (Human) P62136
Entrez Gene ID: (Human) 5499
glycogen metabolic process
regulation of glycogen biosynthetic process
regulation of glycogen catabolic process
protein dephosphorylation
cell cycle
dephosphorylation
lung development
negative regulation of protein binding
circadian regulation of gene expression
regulation of translational initiation by eIF2 alpha dephosphorylation
regulation of circadian rhythm
entrainment of circadian clock by photoperiod
branching morphogenesis of an epithelial tube
cell division
regulation of canonical Wnt signaling pathway
beta-catenin destruction complex disassembly
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
