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Bethyl Laboratories
PP2A Polyclonal Antibody
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PP2A Antibody (A300-732A) in WB
Detection of human and mouse PP2A by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-PP2A antibody (Product # A300-732A) (lot A300-732A-2) used for WB at 0.1 µg/mL. Detection: Chemiluminescence with an exposure time of 30 seconds.
产品信息
A300-732A
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 260 and the C-terminus (residue 309) of Human Protein Phosphatase 2A (PPP2CB, Protein Phosphatase 2, Catalytic Subunit, Beta isoform).
偶联物
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
tris citrate/phosphate, pH 7-8
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Rat, D. melanogaster, Chicken, Bovine, Rabbit and Pig
靶标信息
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. Two transcript variants encoding the same protein have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: phosphatase 2A; PP2A beta; PP2A-beta; PPP2bc; PPP2CB; protein phosphatase 2, catalytic subunit, beta isozyme; protein phosphatase 2a, catalytic subunit, beta isoform; protein phosphatase type 2A catalytic subunit; Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform; testicular tissue protein Li 146; unnamed protein product
基因别名: AI115466; D8Ertd766e; PP2Abeta; PP2Ac; PP2CB; PPP2CB
UniProt ID: (Human) P62714, (Mouse) P62715
Entrez Gene ID: (Human) 5516, (Mouse) 19053
mitotic cell cycle
protein dephosphorylation
apoptotic mitochondrial changes
response to lead ion
regulation of gene expression
negative regulation of gene expression
negative regulation of tumor necrosis factor-mediated signaling pathway
regulation of microtubule polymerization
response to endoplasmic reticulum stress
response to hydrogen peroxide
negative regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of Ras protein signal transduction
response to antibiotic
regulation of neurofibrillary tangle assembly
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