Product References
A mitochondrial iron-responsive pathway regulated by DELE1.
Molecular cell
Sekine Y,Houston R,Eckl EM,Fessler E,Narendra DP,Jae LT,Sekine S
Thu Jun 15 00:00:00 EDT 2023
The Role of Purine Metabolism-Related Genes PPAT and IMPDH1 in the Carcinogenesis of Intrahepatic Cholangiocarcinoma Based on Metabonomic and Bioinformatic Analyses.
Journal of oncology
Liu CJ,Ma ZZ,Gong WZ,Mao XH,Wen HQ,Wang XH
Thu Feb 02 00:00:00 EST 2023
SHMT2 promotes the tumorigenesis of renal cell carcinoma by regulating the m6A modification of PPAT.
Genomics
Huo FC,Xie M,Zhu ZM,Zheng JN,Pei DS
Fri Jul 01 00:00:00 EDT 2022
Therapeutic targeting of glutamate dehydrogenase 1 that links metabolic reprogramming and Snail-mediated epithelial-mesenchymal transition in drug-resistant lung cancer.
Pharmacological research
Wang Q,Wu M,Li H,Rao X,Ao L,Wang H,Yao L,Wang X,Hong X,Wang J,Aa J,Sun M,Wang G,Liu J,Zhou F
Tue Nov 01 00:00:00 EDT 2022
Targeting Subtype-Specific Metabolic Preferences in Nucleotide Biosynthesis Inhibits Tumor Growth in a Breast Cancer Model.
Cancer research
Ogrodzinski MP,Teoh ST,Lunt SY
Fri Jan 15 00:00:00 EST 2021
Mitochondrial NADP+ is essential for proline biosynthesis during cell growth.
Nature metabolism
Tran DH,Kesavan R,Rion H,Soflaee MH,Solmonson A,Bezwada D,Vu HS,Cai F,Phillips JA,DeBerardinis RJ,Hoxhaj G
Thu Apr 01 00:00:00 EDT 2021
Species-Specific Deamidation of RIG-I Reveals Collaborative Action between Viral and Cellular Deamidases in HSV-1 Lytic Replication.
mBio
Huang H,Zhao J,Wang TY,Zhang S,Zhou Y,Rao Y,Qin C,Liu Y,Chen Y,Xia Z,Feng P
Tue Mar 30 00:00:00 EDT 2021
A shift in glutamine nitrogen metabolism contributes to the malignant progression of cancer.
Nature communications
Kodama M,Oshikawa K,Shimizu H,Yoshioka S,Takahashi M,Izumi Y,Bamba T,Tateishi C,Tomonaga T,Matsumoto M,Nakayama KI
Tue Mar 17 00:00:00 EDT 2020
ERK2 Phosphorylates PFAS to Mediate Posttranslational Control of De Novo Purine Synthesis.
Molecular cell
Ali ES,Sahu U,Villa E,O'Hara BP,Gao P,Beaudet C,Wood AW,Asara JM,Ben-Sahra I
Thu Jun 18 00:00:00 EDT 2020
UHMK1 promotes gastric cancer progression through reprogramming nucleotide metabolism.
The EMBO journal
Feng X,Ma D,Zhao J,Song Y,Zhu Y,Zhou Q,Ma F,Liu X,Zhong M,Liu Y,Xiong Y,Qiu X,Zhang Z,Zhang H,Zhao Y,Zhang K,Hong X,Zhang Z
Mon Mar 02 00:00:00 EST 2020
Sideroflexin 4 affects Fe-S cluster biogenesis, iron metabolism, mitochondrial respiration and heme biosynthetic enzymes.
Scientific reports
Paul BT,Tesfay L,Winkler CR,Torti FM,Torti SV
Mon Dec 23 00:00:00 EST 2019
Effect and Mechanism of Tanshinone I on the Radiosensitivity of Lung Cancer Cells.
Molecular pharmaceutics
Yan Y,Su W,Zeng S,Qian L,Chen X,Wei J,Chen N,Gong Z,Xu Z
Mon Nov 05 00:00:00 EST 2018
Effect and Mechanism of Tanshinone I on the Radiosensitivity of Lung Cancer Cells.
Molecular pharmaceutics
Yan Y,Su W,Zeng S,Qian L,Chen X,Wei J,Chen N,Gong Z,Xu Z
Mon Nov 05 00:00:00 EST 2018
Menin enhances c-Myc-mediated transcription to promote cancer progression.
Nature communications
Wu G,Yuan M,Shen S,Ma X,Fang J,Zhu L,Sun L,Liu Z,He X,Huang D,Li T,Li C,Wu J,Hu X,Li Z,Song L,Qu K,Zhang H,Gao P
Fri May 05 00:00:00 EDT 2017
Menin enhances c-Myc-mediated transcription to promote cancer progression.
Nature communications
Wu G,Yuan M,Shen S,Ma X,Fang J,Zhu L,Sun L,Liu Z,He X,Huang D,Li T,Li C,Wu J,Hu X,Li Z,Song L,Qu K,Zhang H,Gao P
Fri May 05 00:00:00 EDT 2017
The mTORC1 Signaling Network Senses Changes in Cellular Purine Nucleotide Levels.
Cell reports
Hoxhaj G,Hughes-Hallett J,Timson RC,Ilagan E,Yuan M,Asara JM,Ben-Sahra I,Manning BD
Tue Oct 31 00:00:00 EDT 2017
The mTORC1 Signaling Network Senses Changes in Cellular Purine Nucleotide Levels.
Cell reports
Hoxhaj G,Hughes-Hallett J,Timson RC,Ilagan E,Yuan M,Asara JM,Ben-Sahra I,Manning BD
Tue Oct 31 00:00:00 EDT 2017
mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle.
Science (New York, N.Y.)
Ben-Sahra I,Hoxhaj G,Ricoult SJH,Asara JM,Manning BD
Fri Feb 12 00:00:00 EST 2016
mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle.
Science (New York, N.Y.)
Ben-Sahra I,Hoxhaj G,Ricoult SJH,Asara JM,Manning BD
Fri Feb 12 00:00:00 EST 2016
Aripiprazole increases NAD(P)H-quinone oxidoreductase-1 and heme oxygenase-1 in PC12 cells.
Journal of neural transmission (Vienna, Austria : 1996)
Kaneko YS,Takayanagi T,Nagasaki H,Kodani Y,Nakashima A,Mori K,Suzuki A,Itoh M,Kondo K,Nagatsu T,Ota M,Ota A
Mon Jun 01 00:00:00 EDT 2015
Aripiprazole increases NAD(P)H-quinone oxidoreductase-1 and heme oxygenase-1 in PC12 cells.
Journal of neural transmission (Vienna, Austria : 1996)
Kaneko YS,Takayanagi T,Nagasaki H,Kodani Y,Nakashima A,Mori K,Suzuki A,Itoh M,Kondo K,Nagatsu T,Ota M,Ota A
Mon Jun 01 00:00:00 EDT 2015
Potent effects of dioscin against obesity in mice.
Scientific reports
Liu M,Xu L,Yin L,Qi Y,Xu Y,Han X,Zhao Y,Sun H,Yao J,Lin Y,Liu K,Peng J
Thu Jan 22 00:00:00 EST 2015
Potent effects of dioscin against obesity in mice.
Scientific reports
Liu M,Xu L,Yin L,Qi Y,Xu Y,Han X,Zhao Y,Sun H,Yao J,Lin Y,Liu K,Peng J
Thu Jan 22 00:00:00 EST 2015
Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Food & function
Dong D,Qi Y,Xu L,Yin L,Xu Y,Han X,Zhao Y,Peng J
Mon Dec 01 00:00:00 EST 2014
Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Food & function
Dong D,Qi Y,Xu L,Yin L,Xu Y,Han X,Zhao Y,Peng J
Mon Dec 01 00:00:00 EST 2014
Prominent steatosis with hypermetabolism of the cell line permissive for years of infection with hepatitis C virus.
PloS one
Sugiyama K,Ebinuma H,Nakamoto N,Sakasegawa N,Murakami Y,Chu PS,Usui S,Ishibashi Y,Wakayama Y,Taniki N,Murata H,Saito Y,Fukasawa M,Saito K,Yamagishi Y,Wakita T,Takaku H,Hibi T,Saito H,Kanai T
Mon Jun 29 00:00:00 EDT 2015
Prominent steatosis with hypermetabolism of the cell line permissive for years of infection with hepatitis C virus.
PloS one
Sugiyama K,Ebinuma H,Nakamoto N,Sakasegawa N,Murakami Y,Chu PS,Usui S,Ishibashi Y,Wakayama Y,Taniki N,Murata H,Saito Y,Fukasawa M,Saito K,Yamagishi Y,Wakita T,Takaku H,Hibi T,Saito H,Kanai T
Mon Jun 29 00:00:00 EDT 2015
Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.
Cancer cell
Mitsuishi Y,Taguchi K,Kawatani Y,Shibata T,Nukiwa T,Aburatani H,Yamamoto M,Motohashi H
Tue Jul 10 00:00:00 EDT 2012
Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.
Cancer cell
Mitsuishi Y,Taguchi K,Kawatani Y,Shibata T,Nukiwa T,Aburatani H,Yamamoto M,Motohashi H
Tue Jul 10 00:00:00 EDT 2012