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Proteintech
PPFIBP2 Polyclonal Antibody
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产品信息
13953-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PPFIBP2 Fusion Protein Ag5064 (577-876 aa encoded by BC021714)
偶联物
形式
Liquid
浓度
0.31 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: IFARQWVSS GHTLLTATPQ DMEKELGIKH PLHRKKLVLA VKAINTKQEE KSALLDHIWV TRWLDDIGLP QYKDQFHESR VDGRMLQYLT VNDLLFLKVT SQLHHLSIKC AIHVLHVNKF NPHCLHRRPA DESNLSPSEV VQWSNHRVME WLRSVDLAEY APNLRGSGVH GGLIILEPRF TGDTLAMLLN IPPQKTLLRR HLTTKFNALI GPEAEQEKRE KMASPAYTPL TTTAKVRPRK LGFSHFGNIR KKKFDESTDY ICPMEPSDGV SDSHRVYSGY RGLSPLDAPE LDGLDQVGQI S (577-876 aa encoded by BC021714)
靶标信息
The PPFIBP2 (PPFIA Binding Protein 2) gene encodes a protein that belongs to the liprin family, which is involved in intracellular signaling and cytoskeletal organization. Located on chromosome 1, PPFIBP2 is primarily known for its role in synaptic function and cell adhesion. The protein interacts with receptor protein tyrosine phosphatases, particularly PTPRF and PTPRD, and plays a critical role in the formation and maintenance of synaptic contacts. PPFIBP2 facilitates the proper localization of synaptic vesicles and synapse-specific proteins, contributing to synaptic stability and plasticity. Disruption of PPFIBP2 expression or function has been linked to neurological disorders, emphasizing its importance in neural communication. Additionally, PPFIBP2 has been implicated in cancer, where it may influence tumor cell adhesion and migration.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Coiled-coil-like protein 1; liprin beta 2; Liprin-beta-2; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2; protein tyrosine phosphatase, receptor-type, F interacting protein, binding protein 2; PTPRF interacting protein, binding protein 2 (liprin beta 2); PTPRF-interacting protein-binding protein 2
基因别名: Cclp1; PPFIBP2
UniProt ID: (Human) Q8ND30, (Mouse) O35711
Entrez Gene ID: (Human) 8495, (Mouse) 19024, (Rat) 308918
