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Abnova
PPFIBP2 Polyclonal Antibody, MaxPab™
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产品信息
H00008495-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PPFIBP2 (NP_003612.1, 1 a.a. approximately 876 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MASDASHALE AALEQMDGII AGTKTGADLS DGTCEPGLAS PASYMNPFPV LHLIEDLRLA LEMLELPQER AALLSQIPGP TAAYIKEWFE ESLSQVNHHS AASNETYQER LARLEGDKES LILQVSVITD QVEAQGEKIR DLEVCLEGHQ VKLNAAEEML QQELLSRTSL ETQKLDLMTE VSELKLKLVG MEKEQREQEE KQRKAEELLQ ELRHLKIKVE ELENERNQYE WKLKATKAEV AQLQEQVALK DAEIERLHSQ LSRTAALHSE SHTERDQEIQ RLKMGMETLL LANEDKDRRI EELTGLLNQY RKVKEIVMVT QGPSERTLSI NEEEPEGGFS KWNATNKDPE ELFKQEMPPR CSSPTVGPPP LPQKSLETRA QKKLSCSLED LRSESVDKCM DGNQPFPVLE PKDSPFLAEH KYPTLPGKLS GATPNGEAAK SPPTICQPDA TGSSLLRLRD TESGWDDTAV VNDLSSTSSG TESGPQSPLT PDGKRNPKGI KKFWGKIRRT QSGNFYTDTL GMAEFRRGGL RATAGPRLSR TRDSKGQKSD ANAPFAQWST ERVCAWLEDF GLAQYVIFAR QWVSSGHTLL TATPQDMEKE LGIKHPLHRK KLVLAVKAIN TKQEEKSALL DHIWVTRWLD DIGLPQYKDQ FHESRVDGRM LQYLTVNDLL FLKVTSQLHH LSIKCAIHVL HVNKFNPHCL HRRPADESNL SPSEVVQWSN HRVMEWLRSV DLAEYAPNLR GSGVHGGLII LEPRFTGDTL AMLLNIPPQK TLLRRHLTTK FNALIGPEAE QEKREKMASP AYTPLTTTAK VRPRKLGFSH FGNIRKKKFD ESTDYICPME PSDGVSDSHR VYSGYRGLSP LDAPELDGLD QVGQIS
靶标信息
The PPFIBP2 (PPFIA Binding Protein 2) gene encodes a protein that belongs to the liprin family, which is involved in intracellular signaling and cytoskeletal organization. Located on chromosome 1, PPFIBP2 is primarily known for its role in synaptic function and cell adhesion. The protein interacts with receptor protein tyrosine phosphatases, particularly PTPRF and PTPRD, and plays a critical role in the formation and maintenance of synaptic contacts. PPFIBP2 facilitates the proper localization of synaptic vesicles and synapse-specific proteins, contributing to synaptic stability and plasticity. Disruption of PPFIBP2 expression or function has been linked to neurological disorders, emphasizing its importance in neural communication. Additionally, PPFIBP2 has been implicated in cancer, where it may influence tumor cell adhesion and migration.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: liprin beta 2; Liprin-beta-2; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2; PTPRF interacting protein, binding protein 2 (liprin beta 2); PTPRF-interacting protein-binding protein 2
基因别名: Cclp1; PPFIBP2
UniProt ID: (Human) Q8ND30
Entrez Gene ID: (Human) 8495
