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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total ASPP1.
This gene encodes a member of the ASPP family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Apoptosis-stimulating of p53 protein 1; Protein phosphatase 1 regulatory subunit 13B; transformation related protein 53 binding protein 2; tumor protein p53 binding protein, 2; tumor protein p53-binding protein, 2
基因别名: AI449786; ASPP1; AW545810; KIAA0771; p85; PPP1R13B; Tp53bp2; Trp53bp2
UniProt ID: (Mouse) Q62415
Entrez Gene ID: (Mouse) 21981