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Invitrogen
PPP1R16B Polyclonal Antibody
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产品信息
PA5-140027
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: RASLSDRTNL YRKEYEGEAI LWQRSAAEDQ RTSTYNGDIR ETRTDQENKD PNPRLEKPVL LSEFPTKI
Highest antigen sequence indentity to the following orthologs: Mouse - 97%, Rat - 96%.
靶标信息
The protein encoded by this gene is membrane-associated and contains five ankyrin repeats, a protein phosphatase-1-interacting domain, and a carboxy-terminal CAAX box domain. Synthesis of the encoded protein is inhibited by transforming growth factor beta-1. The protein may bind to the membrane through its CAAX box domain and may act as a signaling molecule through interaction with protein phosphatase-1. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ankyrin repeat domain protein 4; Ankyrin repeat domain-containing protein 4; CAAX box protein TIMAP; hTIMAP; Protein phosphatase 1 regulatory inhibitor subunit 16B; protein phosphatase 1, regulatory (inhibitor) subunit 16B; protein phosphatase 1, regulatory subunit 16B; TGF-beta-inhibited membrane-associated protein
基因别名: ANKRD4; KIAA0823; PPP1R16B; TIMAP
UniProt ID: (Human) Q96T49
Entrez Gene ID: (Human) 26051
positive regulation of endothelial cell proliferation
regulation of phosphatidylinositol 3-kinase signaling
positive regulation of protein dephosphorylation
negative regulation of protein dephosphorylation
regulation of catalytic activity
regulation of filopodium assembly
establishment of endothelial barrier
negative regulation of peptidyl-serine dephosphorylation
positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
