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Invitrogen
PPP1R9A Polyclonal Antibody
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产品信息
PA3-064
产品规格
已发表种属
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Bacterially expressed coiled-coil domain of rat neurabin I.
偶联物
形式
Liquid
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
PA3-064 detects neurabin-1 from human and rat cells and tissues.
PA3-064 has been successfully used in Western blot and immunofluorescence procedures. By Western blot, this antibody detects an ~123 kDa protein representing neurabin-1 from rat brain extract. Immunofluorescence staining of neurabin-1 in in cultured rat hippocampal cells with PA3-064 results in diffuse cytoplasmic staining.
PA3-064 antigen is bacterially expressed coiled-coil domain of rat neurabin-1.
靶标信息
Neurabin I is a brain-specific protein which contains an F-actin binding domain, a PDZ domain, a transmembrane-protein-interacting-domain, and a coiled-coil region. As its structure suggests, neurabin I is a promiscuous protein binding to F-actin, protein phosphatase 1, TGN38, and p70 S6 kinase. Found exclusively in brain, this protein is highly concentrated in the synapse and has also been shown to be enriched in the lamellipodia of the growth cone during neuronal development. Neurabin I appears to be a bridging protein by targeting other proteins to the synapse or by linking membrane proteins to the actin cytoskeleton.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
