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产品信息
PA5-50734
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:200-1:1,000 | - |
免疫组化（石蜡） (IHC (P)) |
1:50-1:200 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthetic peptide corresponding to a region derived from internal residues of human protein phosphatase 2, regulatory subunit B'', alpha |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1.8 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 40% glycerol |
内含物 |
0.05% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2636186 |
产品详细信息
The antibody detects endogenous levels of total PPP2R3A protein.
靶标信息
Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B'/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holoenzyme. The product of this gene belongs to the B' family. The B' family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B'. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: PP2A subunit B isoform PR72/PR130; PP2A subunit B isoform R3 isoform; PP2A subunit B isoforms B''-PR72/PR130; PP2A subunit B isoforms B72/B130; PP2A, subunit B, R3 isoform; protein phosphatase 2 (formerly 2A), regulatory subunit B'' (PR 72), alpha isoform and (PR 130), beta isoform; protein phosphatase 2 regulatory subunit B'', alpha; protein phosphatase 2, regulatory subunit B'', alpha; Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
基因别名: PPP2R3; PPP2R3A; PR130; PR72
UniProt ID: (Human) Q06190
Entrez Gene ID: (Human) 5523
分子生物学功能:
protein phosphatase
