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Proteintech
PPP3CC Polyclonal Antibody
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产品信息
19653-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PPP3CC Fusion Protein Ag7619 (153-512 aa encoded by BC004864)
偶联物
形式
Liquid
浓度
0.31 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: TDYFTFKQE CRIKYSEQVY DACMETFDCL PLAALLNQQF LCVHGGMSPE ITSLDDIRKL DRFTEPPAFG PVCDLLWSDP SEDYGNEKTL EHYTHNTVRG CSYFYSYPAV CEFLQNNNLL SIIRAHEAQD AGYRMYRKSQ ATGFPSLITI FSAPNYLDVY NNKAAVLKYE NNVMNIRQFN CSPHPYWLPN FMDVFTWSLP FVGEKVTEML VNVLNICSDD ELISDDEAEG STTVRKEIIR NKIRAIGKMA RVFSILRQES ESVLTLKGLT PTGTLPLGVL SGGKQTIETA TVEAVEAREA IRGFSLQHKI RSFEEARGLD RINERMPPRK DSIHAGGPMK SVTSAHSHAA HRSDQGKKAH S (153-512 aa encoded by BC004864)
靶标信息
Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha, calcineurin A-beta, and calcineurin A-gamma (CALNA3), have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95% amino acid identity).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Calcineurin A gamma; Calcineurin, testis-specific catalytic subunit; Calmodulin-dependent calcineurin A subunit gamma isoform; CAM-PRP catalytic subunit; protein phosphatase 2B, catalytic subunit, gamma isoform; protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform; protein phosphatase 3, catalytic subunit, gamma isozyme; Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform
基因别名: CALNA3; Calnc; CNA3; PP2BA gamma; PP2Bgamma; PPP3CC
UniProt ID: (Human) P48454, (Mouse) P48455
Entrez Gene ID: (Human) 5533, (Mouse) 19057
